Dynamic Modeling of GAIT System Reveals Transcriptome Expansion and Translational Trickle Control Device

Post-transcriptional regulatory mechanisms superimpose “fine-tuning” control upon “on-off” switches characteristic of gene transcription. We have exploited computational modeling with experimental validation to resolve an anomalous relationship between mRNA expression and protein synthesis. Differen...

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Hlavní autoři: Yao, Peng, Potdar, Alka A., Arif, Abul, Ray, Partho Sarothi, Mukhopadhyay, Rupak, Willard, Belinda, Xu, Yichi, Yan, Jun, Saidel, Gerald M., Fox, Paul L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3615456/
https://ncbi.nlm.nih.gov/pubmed/22386318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.02.018
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