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An intact connexin N-terminus is required for function but not gap junction formation
The cytoplasmic N-termini of connexins have been implicated in protein trafficking, oligomerization and channel gating. To elucidate the role of the N-terminus in connexin37 (CX37), we studied mutant constructs containing partial deletions of its 23 N-terminal amino acids and a construct with a comp...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752142/ https://ncbi.nlm.nih.gov/pubmed/18664489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.032482 |
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