Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency

X-linked lymphoproliferative disease (XLP) is a rare congenital immunodeficiency that leads to an extreme, usually fatal increase in the number of lymphocytes upon infection with EBV. It is most commonly defined molecularly by loss of expression of SLAM-associated protein (SAP). Despite this, there...

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Главные авторы: Snow, Andrew L., Marsh, Rebecca A., Krummey, Scott M., Roehrs, Philip, Young, Lisa R., Zhang, Kejian, van Hoff, Jack, Dhar, Deepali, Nichols, Kim E., Filipovich, Alexandra H., Su, Helen C., Bleesing, Jack J., Lenardo, Michael J.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2009
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752081/
https://ncbi.nlm.nih.gov/pubmed/19759517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39518
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