Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency

X-linked lymphoproliferative disease (XLP) is a rare congenital immunodeficiency that leads to an extreme, usually fatal increase in the number of lymphocytes upon infection with EBV. It is most commonly defined molecularly by loss of expression of SLAM-associated protein (SAP). Despite this, there...

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Main Authors: Snow, Andrew L., Marsh, Rebecca A., Krummey, Scott M., Roehrs, Philip, Young, Lisa R., Zhang, Kejian, van Hoff, Jack, Dhar, Deepali, Nichols, Kim E., Filipovich, Alexandra H., Su, Helen C., Bleesing, Jack J., Lenardo, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752081/
https://ncbi.nlm.nih.gov/pubmed/19759517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39518
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