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Patients with X-Linked Lymphoproliferative Disease due to BIRC4 Mutation Have Normal Invariant Natural Killer T-Cell Populations

Human invariant natural killer T cells (iNKT cells) are a unique population of T cells that express an invariantly rearranged T-cell receptor (TCR) composed of TCRVα24 and TCRVβ11 chains which recognize glycosphingolipid antigens presented by the CD1d molecule. iNKT cells are absent in patients with...

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Detalhes bibliográficos
Main Authors: Marsh, Rebecca A., Villanueva, Joyce, Kim, Mi-Ok, Zhang, Kejian, Marmer, Dan, Risma, Kimberly A., Jordan, Michael B., Bleesing, Jack J., Filipovich, Alexandra H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729708/
https://ncbi.nlm.nih.gov/pubmed/19398375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.03.517
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