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Lack of Protein S in mice causes embryonic lethal coagulopathy and vascular dysgenesis

Protein S (ProS) is a blood anticoagulant encoded by the Pros1 gene, and ProS deficiencies are associated with venous thrombosis, stroke, and autoimmunity. These associations notwithstanding, the relative risk that reduced ProS expression confers in different disease settings has been difficult to a...

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Detalhes bibliográficos
Main Authors: Burstyn-Cohen, Tal, Heeb, Mary Jo, Lemke, Greg
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752078/
https://ncbi.nlm.nih.gov/pubmed/19729839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39325
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