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Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal
Acetyl-CoA carboxylases (ACC1 and ACC2) catalyze the carboxylation of acetyl-CoA to form malonyl-CoA, an intermediate metabolite that plays a pivotal role in the regulation of fatty acid metabolism. We previously reported that ACC2 null mice are viable, and that ACC2 plays an important role in the r...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1189351/ https://ncbi.nlm.nih.gov/pubmed/16103361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505714102 |
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