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Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal

Acetyl-CoA carboxylases (ACC1 and ACC2) catalyze the carboxylation of acetyl-CoA to form malonyl-CoA, an intermediate metabolite that plays a pivotal role in the regulation of fatty acid metabolism. We previously reported that ACC2 null mice are viable, and that ACC2 plays an important role in the r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Abu-Elheiga, Lutfi, Matzuk, Martin M., Kordari, Parichher, Oh, WonKeun, Shaikenov, Tattym, Gu, Ziwei, Wakil, Salih J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1189351/
https://ncbi.nlm.nih.gov/pubmed/16103361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0505714102
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