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Role of VDR in anti-proliferative effects of calcitriol in tumor-derived endothelial cells and tumor angiogenesis in vivo

Calcitriol (1, 25-dihydroxycholecalciferol), the major active form of vitamin D, is anti-proliferative in tumor cells and tumor-derived endothelial cells (TDEC). These actions of calcitriol are mediated at least in part by vitamin D receptor (VDR), which is expressed in many tissues including endoth...

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Detalhes bibliográficos
Main Authors: Chung, Ivy, Han, Guangzhou, Seshadri, Mukund, Gillard, Bryan M., Yu, Wei-dong, Foster, Barbara A., Trump, Donald L., Johnson, Candace S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2752059/
https://ncbi.nlm.nih.gov/pubmed/19141646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2307
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