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Determining Protein Complex Connectivity Using a Probabilistic Deletion Network Derived from Quantitative Proteomics

Protein complexes are key molecular machines executing a variety of essential cellular processes. Despite the availability of genome-wide protein-protein interaction studies, determining the connectivity between proteins within a complex remains a major challenge. Here we demonstrate a method that i...

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Detalhes bibliográficos
Main Authors: Sardiu, Mihaela E., Gilmore, Joshua M., Carrozza, Michael J., Li, Bing, Workman, Jerry L., Florens, Laurence, Washburn, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751824/
https://ncbi.nlm.nih.gov/pubmed/19806189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0007310
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