High Levels of Tumor Necrosis Factor-α Contribute to Accelerated Loss of Cartilage in Diabetic Fracture Healing

Diabetes interferes with fracture repair; therefore, we investigated mechanisms of impaired fracture healing in a model of multiple low-dose streptozotocin-induced diabetes. Microarray and gene set enrichment analysis revealed an up-regulation of gene sets related to inflammation, including tumor ne...

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Hauptverfasser: Alblowi, Jazia, Kayal, Rayyan A., Siqueria, Michelle, McKenzie, Erin, Krothapalli, Nanarao, McLean, Jody, Conn, Jason, Nikolajczyk, Barbara, Einhorn, Thomas A., Gerstenfeld, Louis, Graves, Dana T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2009
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Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751554/
https://ncbi.nlm.nih.gov/pubmed/19745063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090148
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