An Inducible Cartilage Oligomeric Matrix Protein Mouse Model Recapitulates Human Pseudoachondroplasia Phenotype

Cartilage oligomeric matrix protein (COMP) is a pentameric extracellular protein expressed in cartilage and other musculoskeletal tissues. Mutations in the COMP gene cause pseudoachondroplasia (PSACH), a severe dwarfing condition that has a growth plate chondrocyte pathology. PSACH is characterized...

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Autori principali: Posey, Karen L., Veerisetty, Alka C., Liu, Pieman, Wang, Huiqiu R., Poindexter, Brian J., Bick, Roger, Alcorn, Joseph L., Hecht, Jacqueline T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Investigative Pathology 2009
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Regular Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751552/
https://ncbi.nlm.nih.gov/pubmed/19762713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.090184
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