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Selectivity and potency of cyclin-dependent kinase inhibitors

Members of the cyclin-dependent kinase (CDK) family play key roles in various cellular processes. There are 11 members of the CDK family known till now. CDKs are activated by forming noncovalent complexes with cyclins such as A-, B-, C-, D- (D1, D2, and D3), and E-type cyclins. Each isozyme of this...

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書目詳細資料
Main Authors: Sridhar, Jayalakshmi, Akula, Nagaraju, Pattabiraman, Nagarajan
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2751441/
https://ncbi.nlm.nih.gov/pubmed/16584130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080125
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