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The pharmacokinetics of escitalopram in patients with hepatic impairment
The effect of hepatic impairment on the pharmacokinetics of escitalopram was determined by means of nonlinear mixed effect modeling, considering both the Child-Pugh classification (and its components) and cytochrome P450 2C19 (CYP2C19) activity. Twenty-four subjects were grouped according to their C...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer-Verlag
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2751419/ https://ncbi.nlm.nih.gov/pubmed/16584121 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/aapsj080102 |
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