Orally administered H-Dmt-Tic-Lys-NH-CH(2)-Ph (MZ-2), a potent μ-/δ-opioid receptor antagonist, regulates obese-related factors in mice

Orally active dual μ-/δ-opioid receptor antagonist, H-Dmt-Tic-Lys-NH-CH(2)-Ph (MZ-2) was applied to study body weight gain, fat content, bone mineral density, serum insulin, cholesterol and glucose levels in female ob/ob (B6.V-Lep<ob>/J homozygous) and lean wild mice with or without voluntary...

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Bibliographic Details
Main Authors: Marczak, Ewa D., Jinsmaa, Yunden, Myers, Page H., Blankenship, Terry, Wilson, Ralph, Balboni, Gianfranco, Salvadori, Severo, Lazarus, Lawrence H.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750889/
https://ncbi.nlm.nih.gov/pubmed/19576206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2009.06.041
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