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Mild reduction in the activity of the α-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis
Diminished energy metabolism and reduced activity of brain α-ketoglutarate dehydrogenase complex (KGDHC) occur in a number of neurodegenerative diseases. The relation between diminished KGDHC activity and altered energy metabolism is unknown. The present study tested whether a reduction in the KGDHC...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750872/ https://ncbi.nlm.nih.gov/pubmed/19393030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.05955.x |
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