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Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex

Reduced brain metabolism is an invariant feature of Alzheimer Disease (AD) that is highly correlated to the decline in brain functions. Decreased activities of key tricarboxylic acid cycle (TCA) cycle enzymes may underlie this abnormality and are highly correlated to the clinical state of the patien...

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Main Authors: Shi, Qingli, Xu, Hui, Yu, Haiqiang, Zhang, Nawei, Ye, Yaozu, Estevez, Alvaro G., Deng, Haiteng, Gibson, Gary E.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093839/
https://ncbi.nlm.nih.gov/pubmed/21454586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203018
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