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Inactivation and Reactivation of the Mitochondrial α-Ketoglutarate Dehydrogenase Complex
Reduced brain metabolism is an invariant feature of Alzheimer Disease (AD) that is highly correlated to the decline in brain functions. Decreased activities of key tricarboxylic acid cycle (TCA) cycle enzymes may underlie this abnormality and are highly correlated to the clinical state of the patien...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Biochemistry and Molecular Biology
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3093839/ https://ncbi.nlm.nih.gov/pubmed/21454586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203018 |
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