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Brain [U-(13)C]glucose Metabolism in Mice with Decreased α-Ketoglutarate Dehydrogenase Complex Activity
The activity of the α-ketoglutarate dehydrogenase complex (KGDHC), a mitochondrial enzyme complex which mediates the oxidative decarboxylation of α-ketoglutarate in the TCA cycle, is reduced in Alzheimer’s Disease. We investigated the metabolic effects of a partial KGDHC activity reduction on brain...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3191322/ https://ncbi.nlm.nih.gov/pubmed/21374701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22606 |
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