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Crystal structures of β-neurexin 1 and β-neurexin 2 ectodomains and dynamics of splice insertion sequence 4
Presynaptic neurexins (NRXs) bind to postsynaptic neuroligins (NLs) to form Ca(2+)-dependent protein complexes that bridge neural synapses. NRXs bind NLs through their membrane-proximal LNS domain, which contains a single site of alternative splicing (splice site 4) that gives rise to two isoforms:...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750865/ https://ncbi.nlm.nih.gov/pubmed/18334216 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2007.12.024 |
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