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Radiation Enhances Caspase 3 Cleavage of Rad51 in BRCA2-Defective Cells
After DNA damage, caspases cleave and activate proteins involved in cell death by apoptosis but also cleave and inactivate proteins implicated in DNA repair. Here we report a rapid onset of Rad51 cleavage by caspase 3 in BRCA2-defective mouse and human cells. This rapid cleavage was reduced markedly...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2008
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750858/ https://ncbi.nlm.nih.gov/pubmed/18439040 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1129.1 |
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