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Formulation and in vitro, in vivo evaluation of extended- release matrix tablet of Zidovudine: Influence of combination of hydrophilic and hydrophobic matrix formers

The aim of the present study was to prepare and characterize extended-release matrix tablets of zidovudine using hydrophilic Eudragit RLPO and RSPO alone or their combination with hydrophobic ethyl cellulose. Release kinetics was evaluated by using United States Pharmacopeia (USP)-22 type I dissolut...

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Autors principals: Kuksal, Atul, Tiwary, Ashok K., Jain, Narendra K., Jain, Subheet
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750708/
https://ncbi.nlm.nih.gov/pubmed/16584139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070101
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