In vitro Evaluation of the Effect of Combination of Hydrophilic and Hydrophobic Polymers on Controlled Release Zidovudine Matrix Tablets

The aim of the present study was to prepare and characterize controlled-release matrix tablets of zidovudine using hydrophilic HPMC K4 M or Carbopol 934 alone or in combination with hydrophobic ethyl cellulose. Release kinetics was evaluated by using USP XXIV dissolution apparatus No.2 (paddle) type...

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Main Authors: Ganesh, S., Radhakrishnan, M., Ravi, M., Prasannakumar, B., Kalyani, J.
Format: Artigo
Jezik:Inglês
Izdano: Medknow Publications 2008
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2792557/
https://ncbi.nlm.nih.gov/pubmed/20046771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.44594
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