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Preparation and stability of poly(ethylene glycol) (PEG)ylated octreotide for application to microsphere delivery

The purpose of this study was to prepare poly(ethylene glycol) (PEG)ylated octreotide and investigate the stability against acylation by polyester polymers such as poly(lactic acid) and poly(lactic-co-glycolic acid). Octreotide was modified by reaction with monomethoxy PEG-propionaldehyde (molecular...

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書目詳細資料
Main Authors: Na, Dong Hee, Murty, Santos B., Lee, Kang Choon, Thanoo, B. C., DeLuca, Patrick P.
格式: Artigo
語言:Inglês
出版: Springer-Verlag 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750665/
https://ncbi.nlm.nih.gov/pubmed/15198567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040472
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