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Preparation and stability of poly(ethylene glycol) (PEG)ylated octreotide for application to microsphere delivery
The purpose of this study was to prepare poly(ethylene glycol) (PEG)ylated octreotide and investigate the stability against acylation by polyester polymers such as poly(lactic acid) and poly(lactic-co-glycolic acid). Octreotide was modified by reaction with monomethoxy PEG-propionaldehyde (molecular...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer-Verlag
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750665/ https://ncbi.nlm.nih.gov/pubmed/15198567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt040472 |
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