In vitro and in vivo evaluations of biodegradable implants for hormone replacement therapy: Effect of system design and PK-PD relationship

This investigation evaluated the feasibility of using subdermally implantable devices fabricated by nonconventional 3-dimensional printing technology for controlled delivery of ethinyl estradiol (EE(2)). In vitro release kinetics of EE(2) and in vivo pharmacokinetics pharmacodynamics in ovariectomiz...

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Detaylı Bibliyografya
Asıl Yazarlar: Lin, Senshang, Chao, Pi-Yun, Chien, Yie W., Sayani, Amyn, Kumar, Sandeep, Mason, Michelle, West, Thomas, Yang, Alice, Monkhouse, Donald
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer-Verlag 2001
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750581/
https://ncbi.nlm.nih.gov/pubmed/14727875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt020316
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