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Floating granules of ranitidine hydrochloride-gelucire 43/01: Formulation optimization using factorial design
The purpose of this research was to develop and optimize a controlled-release multiunit floating system of a highly water soluble drug, ranitidine HCl, using Compritol, Gelucire 50/13, and Gelucire 43/01 as lipid carriers. Ranitidine HCl-lipid granules were prepared by the melt granulation technique...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Springer-Verlag
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750366/ https://ncbi.nlm.nih.gov/pubmed/17622108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802030 |
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