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Preparation and evaluation of diltiazem hydrochloride-gelucire 43/01 floating granules prepared by melt granulation

The basic objective of this study was to explore the application of Gelucire 43/01 for the design of multi-unit floating systems of a highly water-soluble drug diltiazem HCl. Diltiazem HCl-Gelucire 43/01 granules were prepared by melt granulation technique. The granules were evaluated for in vitro a...

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Detalhes bibliográficos
Main Authors: Shimpi, Shyam, Chauhan, Bhaskar, Mahadik, K. R., Paradkar, Anant
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750266/
https://ncbi.nlm.nih.gov/pubmed/15760076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050343
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