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Preparation and evaluation of diltiazem hydrochloride-gelucire 43/01 floating granules prepared by melt granulation
The basic objective of this study was to explore the application of Gelucire 43/01 for the design of multi-unit floating systems of a highly water-soluble drug diltiazem HCl. Diltiazem HCl-Gelucire 43/01 granules were prepared by melt granulation technique. The granules were evaluated for in vitro a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer-Verlag
2004
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2750266/ https://ncbi.nlm.nih.gov/pubmed/15760076 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt050343 |
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