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Floating granules of ranitidine hydrochloride-gelucire 43/01: Formulation optimization using factorial design

The purpose of this research was to develop and optimize a controlled-release multiunit floating system of a highly water soluble drug, ranitidine HCl, using Compritol, Gelucire 50/13, and Gelucire 43/01 as lipid carriers. Ranitidine HCl-lipid granules were prepared by the melt granulation technique...

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Detalhes bibliográficos
Main Authors: Patel, Dasharath M., Patel, Natavarlal M., Patel, Viral F., Bhatt, Darshini A.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750366/
https://ncbi.nlm.nih.gov/pubmed/17622108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0802030
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