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Physicohemical characterization of the freezing behavior of mannitol-human serum albumin formulations

The goal of the study was to analyze the impact of human serum albumin (HSA) quality (stabilized or nonstabilized HSA), the addition of NaCl, and the HSA stabilizers Naoctanoate and Na-N-acetyltryptophanate on the freezing behavior of mannitol-HSA formulations. The focus was on crystallization, Tg&#...

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Detalles Bibliográficos
Main Authors: Hawe, Andrea, Friess, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750331/
https://ncbi.nlm.nih.gov/pubmed/17285745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070494
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