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Physicohemical characterization of the freezing behavior of mannitol-human serum albumin formulations

The goal of the study was to analyze the impact of human serum albumin (HSA) quality (stabilized or nonstabilized HSA), the addition of NaCl, and the HSA stabilizers Naoctanoate and Na-N-acetyltryptophanate on the freezing behavior of mannitol-HSA formulations. The focus was on crystallization, Tg&#...

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Hlavní autoři: Hawe, Andrea, Friess, Wolfgang
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750331/
https://ncbi.nlm.nih.gov/pubmed/17285745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt070494
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