Proofreading dynamics of a processive DNA polymerase

Replicative DNA polymerases present an intrinsic proofreading activity during which the DNA primer chain is transferred between the polymerization and exonuclease sites of the protein. The dynamics of this primer transfer reaction during active polymerization remain poorly understood. Here we descri...

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Autors principals: Ibarra, Borja, Chemla, Yann R, Plyasunov, Sergey, Smith, Steven B, Lázaro, José M, Salas, Margarita, Bustamante, Carlos
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750014/
https://ncbi.nlm.nih.gov/pubmed/19661923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.219
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