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Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation
This review deals with the pharmacological properties of an alkylated monosaccharide mimetic, N-butyldeoxynojirimycin (NB-DNJ). This compound is of pharmacogenetic interest because one of its biological effects in mice – impairment of spermatogenesis, leading to male infertility – depends greatly on...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2749735/ https://ncbi.nlm.nih.gov/pubmed/18518850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.6.717 |
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