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Differential sensitivity of mouse strains to an N-alkylated imino sugar: glycosphingolipid metabolism and acrosome formation

This review deals with the pharmacological properties of an alkylated monosaccharide mimetic, N-butyldeoxynojirimycin (NB-DNJ). This compound is of pharmacogenetic interest because one of its biological effects in mice – impairment of spermatogenesis, leading to male infertility – depends greatly on...

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Autori principali: van der Spoel, Aarnoud C, Mott, Richard, Platt, Frances M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749735/
https://ncbi.nlm.nih.gov/pubmed/18518850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/14622416.9.6.717
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