The Alkylated Imino Sugar, n-(n-Nonyl)-Deoxygalactonojirimycin, Reduces the Amount of Hepatitis B Virus Nucleocapsid in Tissue Culture

n-(n-Nonyl)-deoxygalactonojirimycin (n,n-DGJ), an alkylated imino sugar, reduces the amount of HBV DNA produced within the stably transfected HBV-producing HepG2.2.15 line in culture and is under consideration for development as a human therapeutic. n,n-DGJ does not appear to inhibit HBV DNA polymer...

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Detalhes bibliográficos
Main Authors: Lu, Xuanyong, Tran, Trang, Simsek, Ender, Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC254279/
https://ncbi.nlm.nih.gov/pubmed/14581530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.22.11933-11940.2003
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