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The Alkylated Imino Sugar, n-(n-Nonyl)-Deoxygalactonojirimycin, Reduces the Amount of Hepatitis B Virus Nucleocapsid in Tissue Culture

n-(n-Nonyl)-deoxygalactonojirimycin (n,n-DGJ), an alkylated imino sugar, reduces the amount of HBV DNA produced within the stably transfected HBV-producing HepG2.2.15 line in culture and is under consideration for development as a human therapeutic. n,n-DGJ does not appear to inhibit HBV DNA polymer...

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Udgivet i:J Virol
Principais autores: Lu, Xuanyong, Tran, Trang, Simsek, Ender, Block, Timothy M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2003
Fag:
Replication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254279/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14581530/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.22.11933-11940.2003
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