Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents

One function of N-linked glycans is to assist in the folding of glycoproteins by mediating interactions of the lectin-like chaperone proteins calnexin and calreticulin with nascent glycoproteins. These interactions can be prevented by inhibitors of the α-glucosidases, such as N-butyl-deoxynojirimyci...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Zitzmann, Nicole, Mehta, Anand S., Carrouée, Sandra, Butters, Terry D., Platt, Frances M., McCauley, John, Blumberg, Baruch S., Dwek, Raymond A., Block, Timothy M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18380/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518544/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11878
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