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Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus: Implications for the development of broad spectrum anti-hepatitis virus agents

One function of N-linked glycans is to assist in the folding of glycoproteins by mediating interactions of the lectin-like chaperone proteins calnexin and calreticulin with nascent glycoproteins. These interactions can be prevented by inhibitors of the α-glucosidases, such as N-butyl-deoxynojirimyci...

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Autors principals: Zitzmann, Nicole, Mehta, Anand S., Carrouée, Sandra, Butters, Terry D., Platt, Frances M., McCauley, John, Blumberg, Baruch S., Dwek, Raymond A., Block, Timothy M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC18380/
https://ncbi.nlm.nih.gov/pubmed/10518544
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