The Pathogen Protein EspF(U) Hijacks Actin Polymerization Using Mimicry and Multivalency

Enterohemorrhagic E. coli (EHEC) attaches to the intestine through actin pedestals that are formed when the bacterium injects the protein EspF(U) into host cells1. EspF(U) potently activates the host WASP (Wiskott-Aldrich syndrome protein) family of actin-nucleating factors, which are normally activ...

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Autori principali: Sallee, Nathan A., Rivera, Gonzalo M., Dueber, John E., Vasilescu, Dan, Mullins, R. Dyche, Mayer, Bruce J., Lim, Wendell A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749708/
https://ncbi.nlm.nih.gov/pubmed/18650806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07170
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