The Pathogen Protein EspF(U) Hijacks Actin Polymerization Using Mimicry and Multivalency

Enterohemorrhagic E. coli (EHEC) attaches to the intestine through actin pedestals that are formed when the bacterium injects the protein EspF(U) into host cells1. EspF(U) potently activates the host WASP (Wiskott-Aldrich syndrome protein) family of actin-nucleating factors, which are normally activ...

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Bibliografiske detaljer
Main Authors: Sallee, Nathan A., Rivera, Gonzalo M., Dueber, John E., Vasilescu, Dan, Mullins, R. Dyche, Mayer, Bruce J., Lim, Wendell A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749708/
https://ncbi.nlm.nih.gov/pubmed/18650806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07170
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