Yeast lifespan extension by depletion of 60S ribosomal subunits is mediated by Gcn4

In nearly every organism studied, reduced caloric intake extends lifespan. In yeast, lifespan extension from dietary restriction is thought to be mediated by the highly-conserved, nutrient-responsive TOR, PKA and Sch9 kinases. These kinases coordinately regulate various cellular processes including...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Steffen, Kristan K., MacKay, Vivian L., Kerr, Emily O., Tsuchiya, Mitsuhiro, Hu, Di, Fox, Lindsay A., Dang, Nick, Johnston, Elijah D., Oakes, Jonathan A., Tchao, Bie N., Pak, Diana N., Fields, Stanley, Kennedy, Brian K., Kaeberlein, Matt
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2008
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749658/
https://ncbi.nlm.nih.gov/pubmed/18423200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.02.037
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