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Increased Life Span due to Calorie Restriction in Respiratory-Deficient Yeast
A model for replicative life span extension by calorie restriction (CR) in yeast has been proposed whereby reduced glucose in the growth medium leads to activation of the NAD(+)–dependent histone deacetylase Sir2. One mechanism proposed for this putative activation of Sir2 is that CR enhances the ra...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1287956/ https://ncbi.nlm.nih.gov/pubmed/16311627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0010069 |
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