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Sir2-Independent Life Span Extension by Calorie Restriction in Yeast

Calorie restriction slows aging and increases life span in many organisms. In yeast, a mechanistic explanation has been proposed whereby calorie restriction slows aging by activating Sir2. Here we report the identification of a Sir2-independent pathway responsible for a majority of the longevity ben...

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Publicado en:PLoS Biol
Autores principales: Kaeberlein, Matt, Kirkland, Kathryn T, Fields, Stanley, Kennedy, Brian K
Formato: Artigo
Lenguaje:Inglês
Publicado: PLOS 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC514491/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15328540/
https://ncbi.nlm.nih.govhttps://doi.org/10.1371/journal.pbio.0020296
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