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Extension of chronological life span in yeast by decreased TOR pathway signaling

Chronological life span (CLS) in Saccharomyces cerevisiae, defined as the time cells in a stationary phase culture remain viable, has been proposed as a model for the aging of post-mitotic tissues in mammals. We developed a high-throughput assay to determine CLS for ∼4800 single-gene deletion strain...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Powers, R. Wilson, Kaeberlein, Matt, Caldwell, Seth D., Kennedy, Brian K., Fields, Stanley
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356109/
https://ncbi.nlm.nih.gov/pubmed/16418483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1381406
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