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Renal cells activate the platelet receptor CLEC-2 through podoplanin

We have recently shown that the C-type lectin-like receptor, CLEC-2, is expressed on platelets and that it mediates powerful platelet aggregation by the snake venom toxin, rhodocytin. In addition, we have provided indirect evidence for an endogenous ligand for CLEC-2 in renal cells expressing human...

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Bibliografiska uppgifter
Huvudupphovsmän: Christou, Charita M., Pearce, Andrew C., Watson, Aleksandra A., Mistry, Anita R., Pollitt, Alice Y., Fenton-May, Angharad E., Johnson, Louise A., Jackson, David G., Watson, Steve P., O'Callaghan, Chris A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749330/
https://ncbi.nlm.nih.gov/pubmed/18215137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20071216
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