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Crystal structure of rhodocytin, a ligand for the platelet-activating receptor CLEC-2
Binding of the snake venom protein rhodocytin to CLEC-2, a receptor on the surface of human platelets, initiates a signaling cascade leading to platelet activation and aggregation. We have previously solved the structure of CLEC-2. The 2.4 Å resolution crystal structure of rhodocytin presented here...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2525532/ https://ncbi.nlm.nih.gov/pubmed/18583525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.035568.108 |
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