NHERF3 (PDZK1) Contributes to Basal and Calcium Inhibition of NHE3 Activity in Caco-2BBe Cells

Elevated intracellular Ca(2+) ([Ca(2+)](i)) inhibition of NHE3 is reconstituted by NHERF2, but not NHERF1, by a mechanism involving the formation of multiprotein signaling complexes. To further evaluate the specificity of the NHERF family in calcium regulation of NHE3 activity, the current study det...

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Autors principals: Zachos, Nicholas C., Li, Xuhang, Kovbasnjuk, Olga, Hogema, Boris, Sarker, Rafiquel, Lee, Luke J., Li, Min, de Jonge, Hugo, Donowitz, Mark
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Mechanisms of Signal Transduction
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749145/
https://ncbi.nlm.nih.gov/pubmed/19535329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.012641
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