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Localizing the Membrane Binding Region of Group VIA Ca(2+)-independent Phospholipase A(2) Using Peptide Amide Hydrogen/Deuterium Exchange Mass Spectrometry

The Group VIA-2 Ca(2+)-independent phospholipase A(2) (GVIA-2 iPLA(2)) is composed of seven consecutive N-terminal ankyrin repeats, a linker region, and a C-terminal phospholipase catalytic domain. No structural information exists for this enzyme, and no information is known about the membrane bindi...

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Hlavní autoři: Hsu, Yuan-Hao, Burke, John E., Li, Sheng, Woods, Virgil L., Dennis, Edward A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749140/
https://ncbi.nlm.nih.gov/pubmed/19556238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.021857
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