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Protein Kinase Cθ Regulates Stability of the Peripheral Adhesion Ring Junction and Contributes to the Sensitivity of Target Cell Lysis by CTL

Destruction of virus-infected cells by CTL is an extremely sensitive and efficient process. Our previous data suggest that LFA-1-ICAM-1 interactions in the peripheral supramolecular activation cluster (pSMAC) of the immunological synapse mediate formation of a tight adhesion junction that might cont...

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Bibliographic Details
Main Authors: Beal, Allison M., Anikeeva, Nadia, Varma, Rajat, Cameron, Thomas O., Norris, Philip J., Dustin, Michael L., Sykulev, Yuri
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748977/
https://ncbi.nlm.nih.gov/pubmed/18802085
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