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A mutation within the transmembrane domain of melanosomal protein Silver (Pmel17) changes lumenal fragment interactions
Melanocytes synthesize and store melanin within tissue-specific organelles, the melanosomes. Melanin deposition takes place along fibrils found within these organelles and fibril formation is known to depend on trafficking of the membrane glycoprotein Silver/Pmel17. However, correctly targeted, full...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748924/ https://ncbi.nlm.nih.gov/pubmed/19679373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejcb.2009.07.001 |
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