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Raf-independent, PP2A-dependent MEK Activation in Response to ERK Silencing
Biological roles of ERK and MEK in signal transduction have been controversial. The aim of the current study was to determine the role of ERK1/2 in signaling through the ERK-MAPK cascade by using RNAi methodology. Transient transfection of erk1 or erk2 siRNA decreased the respective protein level to...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2748906/ https://ncbi.nlm.nih.gov/pubmed/19465001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.082 |
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