Enhanced clonogenic survival induced by protein tyrosine phosphatase (PTP) inhibition after Cr(VI) exposure is mediated by c-Raf and Ras activity

Our recent studies showed that maintenance of protein tyrosine phosphorylation by PTP inhibition enhanced cell growth, clonogenic survival, and mutagenesis after a single low-level Cr(VI) exposure, thereby suggesting that tyrosine phosphorylation-dependent signaling may govern inappropriate survival...

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Hauptverfasser: Bae, Dongsoon, Camilli, Tura C., Ha, Ngoc-Tram, Ceryak, Susan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673100/
https://ncbi.nlm.nih.gov/pubmed/19167484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2009.01.011
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