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Insertion of a Bulky Rhodium Complex into a DNA Cytosine-Cytosine Mismatch: An NMR Solution Study

The bulky octahedral complex, Rh(bpy)(2)chrysi(3+) (chrysi = 5, 6- chrysenequinone diimine), binds single base mismatches in a DNA duplex with micromolar binding affinities and high selectivity. Here we present an NMR solution study to characterize the binding mode of this bulky metal complex with i...

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Detalhes bibliográficos
Main Authors: Cordier, Christine, Pierre, Valerie C., Barton, Jacqueline K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2748819/
https://ncbi.nlm.nih.gov/pubmed/17877349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0739436
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